Completely replace the transformation matrix of a three.js object/mesh

Questions
1

Create object

A three.js mesh object is created:

	var geometry = new THREE.BufferGeometry();

	var standardMaterial = new THREE.MeshStandardMaterial( {/* inputs */ } );

	var mesh = new THREE.Mesh( geometry, standardMaterial );

	// Then mesh is added as an object to 3D scene.

Set transformation matrix

I intend to set the transformation matrix of the object:

			object = ... // Is already created and passed around.

			const pkm = ... // Containing 16 numbers, equivalent of a 4x4 matrix.

			var matrix = new THREE.Matrix4();

			matrix.set(
				pkm.X00, pkm.X01, pkm.X02, pkm.X03,
				pkm.X10, pkm.X11, pkm.X12, pkm.X13,
				pkm.X20, pkm.X21, pkm.X22, pkm.X23,
				pkm.X30, pkm.X31, pkm.X32, pkm.X33,
			);

			object.applyMatrix4( matrix );
			object.updateMatrixWorld( true );

Problem

The problem is that the above approach of setting transformation matrix just multiplies the new matrix into the previous matrix of the object. But we want the previous matrix to be completely replaced by the new matrix.

What is the best practice - most robust way - to replace the previous matrix of a three.js object/mesh with a completely new one?

2

What about:

object.matrix.set(
	pkm.X00, pkm.X01, pkm.X02, pkm.X03,
	pkm.X10, pkm.X11, pkm.X12, pkm.X13,
	pkm.X20, pkm.X21, pkm.X22, pkm.X23,
	pkm.X30, pkm.X31, pkm.X32, pkm.X33,
);

and set matrixAutoUpdate to false.