Yes, react-three-fiber is probably the most reasonable and popular way of using three with react (plus it’s very good for big / complex projects)
Anything that uses WebGL to render 3D will most likely be affected (the limits aren’t imposed by three / WebGL, but by the built-in WebView browser. Whether the project uses vanilla / react / vue / angular would be irrelevant.)
You can try using expo-gl - but personally I don’t have enough experience with it, so hard for me to tell if / what development challenges would appear there (it doesn’t seem to use WebView so the memory limitations wouldn’t affect it though.)